GRIN3A and MAPT stimulate nerve overgrowth in macrodactyly
نویسندگان
چکیده
منابع مشابه
Macrodactyly.
We report the results of the treatment of 23 patients with macrodactyly. Eighteen had a two-stage bulk-reducing (defatting) procedure; phalangectomy was used to shorten the digits. At a mean follow-up of nine years (2 to 12), two patients had been lost to follow-up, and three await a second-stage procedure. Good cosmetic correction was achieved in 12 patients, with satisfactory results in seven...
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After optic nerve injury in mature mammals, retinal ganglion cells (RGCs) are normally unable to regenerate their axons and undergo delayed apoptosis. However, if the lens is damaged at the time of nerve injury, many RGCs survive axotomy and regenerate their axons into the distal optic nerve. Lens injury induces macrophage activation, and we show here that factors secreted by macrophages stimul...
متن کاملCongenital macrodactyly: a clinical study.
Congenital macrodactyly is a rare congenital malformation characterised by progressive enlargement of all mesenchymal elements of a digit. The present study is an attempt to draw the attention towards the similarities and differences between macrodactyly of the hand and foot. Radiographical, operative findings and histopathological examination of five cases are included in the present study. Em...
متن کاملLipofibromatous Hamartoma of the Median Nerve in Association with or without Macrodactyly.
Lipofibromatous hamartoma is a rare tumour-like condition involving the peripheral nerves, particularly the median nerve. It commonly affects the volar aspect of the hands, wrists and forearms of young adults. Most patients present either early with macrodactyly or later with a forearm mass lesion or symptoms consistent with compressive neuropathy of the involved nerve. The clinical and histomo...
متن کاملA Case of Macrodactyly
S., a Hindu girl, aged 10 years, of the village Saraiyan, in Ghazipnr district, was admitted into the hospital with abnormal enlargement of the right middle finger. She came to the hospital for its removal, as she had been feeling its weight. It is seven and a half inches in length and seven and a half inches in diameter at its thickest part. The left middle finger is three inches in length and...
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ژورنال
عنوان ژورنال: Molecular Medicine Reports
سال: 2016
ISSN: 1791-2997,1791-3004
DOI: 10.3892/mmr.2016.5923